Hereditary risk
Carriage of mutations increases the risk of thrombosis during provocations (surgeries, hormonal contraceptives, pregnancy, flights) - knowledge of the status changes prevention: selection of contraception, heparin prophylaxis during pregnancy and operations. Indications: thrombosis before 50 years of age, family history, repeated pregnancy losses. The result does not change - it is submitted once.
When is it appointed?
- preparation for operations is a mandatory block;
- taking anticoagulants (warfarin - INR) - dose control;
- thrombosis and miscarriage - search for thrombophilia;
- bleeding: bruises, nose, gums;
- pregnancy - planned control of hemostasis.
Coagulation system
Hemostasis balances between bleeding and thrombosis: screening tests (prothrombin/INR, aPTT, fibrinogen) evaluate the coagulation cascade, D-dimer catches active thrombus formation, special tests (lupus anticoagulant, genetics of thrombophilia) look for the cause of repeated thrombosis and pregnancy losses. Before any operation, a coagulogram is mandatory - hidden disorders are detected before the incision, and not during it.
