Chromosome pair verification
The carrier of a balanced translocation is healthy, but some of his germ cells carry an unbalanced set - hence the loss of pregnancy. The identified restructuring changes the strategy: IVF with preimplantation genetic testing selects embryos with a normal set. The test is also required for azoospermia (Klinefelter syndrome). Results in 2-3 weeks with consultation.
When is it appointed?
- two or more miscarriages - karyotypes of the couple;
- infertility of unknown origin, severe spermogram abnormalities;
- planning pregnancy with a complicated medical history;
- high homocysteine - genetics of the folate cycle;
- comprehensive pre-gravid preparation.
Genetics of reproduction
Part of pregnancy losses and infertility is recorded in chromosomes and genes: balanced translocations in parents (karyotype), polymorphisms of the folate cycle and thrombophilia affect gestation - and almost all of this is manageable with a known status: from preparation with folates in active form to IVF with preimplantation testing. Genetic tests are taken once in a lifetime and consciously change the couple’s strategy.
