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Microcephaly in a child: causes, examination and prognosis

Other names: Микроцефалия, маленькая голова у ребёнка, маленькая окружность головы, уменьшенный объём черепа у новорождённого, микроцефалия у грудничка

Microcephaly is not an independent disease, but a sign: the child’s head circumference is significantly less than the average for his age and gender. The skull grows with the brain, so a reduced head size almost always reflects underdevelopment or damage to brain tissue. Microcephaly can be congenital, when it is noticed at birth, and acquired, when the head grows too slowly in the first months and years. There are many reasons: genetic characteristics, previous intrauterine infections, oxygen starvation during childbirth, metabolic disorders. One measurement in itself does not prove anything: the dynamics of head growth, the size of the parents and how the child develops are important.

🧾 МКБ-10: Q02 🏥 Where it is treated: 8 The head is smaller than the age normDynamics are important, not just one measurementNeed to find a reason
👨‍⚕️ Which doctor
Pediatrician, pediatric neurologist, geneticist, infectious disease specialist
🔬 Diagnostics
Measuring head circumference using centile tables, neurosonography, MRI of the brain, EEG, examination for congenital infections, karyotyping and genetic tests
💊 Treatment
There is no treatment to increase brain volume; treat the cause if it exists and carry out early developmental rehabilitation
📈 Prognosis
Depends on the cause and degree: from normal development in the familial form to severe delay
⚠️ At risk
Intrauterine infections, alcohol and drugs during pregnancy, severe hypoxia during childbirth, hereditary syndromes, consanguineous marriage
⏱ When to see a doctor
Scheduled, but the examination should not be postponed

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Окружность головы почти не увеличивается от месяца к месяцу
  • Судороги, замирания, серии вздрагиваний
  • Ребёнок утратил ранее приобретённые навыки
  • Выраженное отставание: не держит голову к трём месяцам, не сидит к девяти
  • Плохое сосание, частые срыгивания и остановка прибавки веса
  • Нарушения зрения и слуха, отсутствие реакции на голос и лицо

How to estimate head size

Head circumference is measured with a measuring tape at the widest part - above the eyebrows and through the occipital protuberance. The result is plotted on a centile graph corresponding to the age, gender and date of birth of the child. Microcephaly is spoken of when the rate is significantly below the average for this age. Much more important than the figure obtained once is how the indicator changes over time: if the head grows parallel to the schedule, and the child develops normally, we are often talking about a constitutional feature. The parents' heads must also be measured.

  • Measurement at the widest circumference of the head
  • Score using centile tables for age and gender
  • Accounting for the date of birth in premature infants
  • Dynamics over several months is required
  • Measuring parents' head circumference
  • Comparison with the height and weight of the child

Reasons

Congenital microcephaly is most often associated with genetic disorders and intrauterine exposures. Among the infections, cytomegalovirus, toxoplasmosis, rubella, herpes and Zika virus are important. A separate group of causes are alcohol, drugs and certain medications taken during pregnancy, as well as severe malnutrition and uncontrolled phenylketonuria in the mother. The acquired form develops after severe hypoxia during childbirth, meningitis, encephalitis, traumatic brain injury, or against the background of hereditary metabolic diseases. Sometimes the cause cannot be determined.

  • Genetic syndromes and chromosomal disorders
  • Intrauterine infections: CMV, toxoplasmosis, rubella, Zika
  • Alcohol and drugs during pregnancy
  • Severe hypoxia and cerebral ischemia during childbirth
  • Past meningitis or encephalitis
  • Hereditary metabolic diseases
  • Family (constitutional) small head

How does this affect development?

The range is very wide. In the familial form, a child with a small head develops completely normally, learns on par with peers and does not need treatment. With microcephaly associated with brain damage, speech and motor delays, learning difficulties, epilepsy, visual and hearing impairment, and changes in muscle tone are possible. The prognosis is determined not by a centimeter of circumference, but by MRI data and the child’s actual skills. Therefore, it is important for parents not to look for the answer in one number, but to observe and work with the child.

  • Family form - development is normal
  • Delayed motor and speech development due to brain damage
  • Epileptic seizures
  • Spasticity or decreased muscle tone
  • Learning and behavioral difficulties
  • Visual and hearing impairment

Survey

The examination begins with detailed collection of information about pregnancy, childbirth and family, examination by a pediatrician and neurologist. Neurosonography through the fontanel is available and safe for infants and shows gross malformations of the brain and calcifications characteristic of congenital infections. MRI of the brain provides the most accurate picture of the structure of the cortex and white matter. Testing for congenital infections is especially important in the first months of life. If a hereditary cause is suspected, karyotyping and modern genetic tests are prescribed, and an EEG is needed for seizures and freezing.

  • Examination by a pediatrician and pediatric neurologist
  • Neurosonography through the large fontanel
  • MRI of the brain
  • EEG for suspected seizures
  • Screening for congenital infections
  • Karyotyping and genetic counseling
  • Vision and hearing tests

What can you do

There are no drugs that would increase brain volume, and promises of this kind should be alarming. Real help consists of treatment of the identified cause, control of seizures, good nutrition and early intervention: classes with a speech therapist and speech pathologist, physical therapy, work with an occupational therapist. The earlier developmental activities begin, the better the child uses the available opportunities. The family benefits from genetic counseling when planning the next pregnancy, and during pregnancy, prevention of infections, taking folic acid and completely abstaining from alcohol.

  • Treatment of an established cause
  • Anticonvulsant therapy as prescribed by a neurologist
  • Early developmental intervention and sessions with specialists
  • Physical therapy and motor skills work
  • Monitoring nutrition and weight gain
  • Family genetic counseling
  • Preventing infections and avoiding alcohol during pregnancy

Services and prices for this diagnosis

Based on official price lists of Tashkent clinics. The exact cost is determined after examination.

Frequently asked questions: Microcephaly

Does microcephaly always mean mental retardation?+
No. If the head is small, but grows evenly, and the child masters skills according to age, more often we are talking about a family trait. The prognosis is determined by the results of MRI, the presence of seizures and actual development, and not just centimeters.
Is it possible to enlarge a child's head with medications or massage?+
No. Neither medications, nor massage, nor physical procedures affect brain volume. Treatment of the identified cause, control of seizures, nutritious nutrition and regular developmental classes with specialists are useful.
When is microcephaly noticed?+
Sometimes a reduction in the head can be seen on an ultrasound during pregnancy or immediately after birth. The acquired form is revealed later - when, during routine examinations, the pediatrician notices that the head circumference has ceased to catch up with the age graph.
Will this happen again in the next child?+
Depends on the reason. If the infection is infectious, the risk of recurrence is low if the infection has persisted and is no longer active. In hereditary forms, it can be significant, so genetic counseling is recommended for the family before the next pregnancy.
What activities help a child with microcephaly?+
Early intervention: physical therapy and work on gross and fine motor skills, classes with a speech therapist and speech pathologist, development of self-care skills. The program is designed individually, taking into account the age and capabilities of the child.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated microcephaly в Ташкенте

Rate размеры головы правильно можно только по центильным таблицам и в динамике, поэтому нужен осмотр педиатра и невролога. Clinics Ташкента с педиатрами и неврологами:

st. Mirzaeva 50, Yunusabad 17, Yunusabad district, Tashkent Landmark: opposite the Nazar M...
M Turkiston 🚶 1.5 km
M Yunusobod 🚶 2.0 km
M Shahriston 🚶 2.8 km
🚌 Nearest bus stop 🚶 100 m · buses: 7
Mon–Fri:09:00–18:00
Closed now
Mukimiy street 144/1, Chilanzar district, Tashkent Landmarks: Novza metro station (former...
M Novza 🚶 400 m
M Mirzo Ulug'bek 🚶 650 m
M Milliy bog' 🚶 1.3 km
🚌 Nearest bus stop 🚶 170 m · buses: 9Т, 56
Mon–Fri:09:00–18:00
Closed now
Branch No. 3: Birlashgan street, opposite the 4-City Clinical Hospital
M Tuzel 🚶 750 m
M Yashnobod 🚶 800 m
M Texnopark 🚶 1.4 km
🚌 Nearest bus stop 🚶 200 m · buses: 22
Пн–Sat:07:00–20:00
Closed now
Tashkent, Mirabad district, st. Oybek, 34d
M Toshkent 🚶 550 m
M Oybek 🚶 850 m
M Kosmonavtlar 🚶 1.3 km
🚌 Nearest bus stop 🚶 150 m · buses: 22
Tashkent, Yakkasaray district, st. Sh.Rustaveli, 109 A
M Oybek 🚶 2.4 km
M Kosmonavtlar 🚶 2.6 km
M Novza 🚶 2.9 km
🚌 Nearest bus stop 🚶 70 m · buses: 2, 11, 12, 40, 45, 47
Пн–Sat:08:00–17:30
Closed now
Tashkent, Khamza district, M. Ulugbek Ave., 5d
M Mashinasozlar 🚶 1.1 km
M Do'stlik 🚶 1.1 km
M Hamid Olimjon 🚶 1.6 km
🚌 Nearest bus stop 🚶 50 m · buses: 28
Mon–Fri:09:00–17:00
Closed now
Tashkent, Chilanzar district, st. Foziltepa, 40d
M Olmazor 🚶 3.2 km
M Chilonzor 🚶 3.2 km
M Mirzo Ulug'bek 🚶 3.6 km
🚌 Nearest bus stop 🚶 320 m · buses: 13, 17T, 33
Mon–Fri:09:00–17:00
Closed now
Tashkent, Yashnobod district, st. Dzharkurgon, 37d
M Quyliq 🚶 1.4 km
M Matonat 🚶 1.6 km
M Yangiobod 🚶 1.7 km
🚌 Nearest bus stop 🚶 60 m · buses: 15, 26
Mon–Fri:09:00–17:00
Closed now

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

Other diseases: Pediatrics

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