Restoration of the bladder mucosa
With interstitial cystitis and recurrent infections, the glycosaminoglycan layer that protects the bladder wall from urine is damaged; instillations of hyaluronic acid and chondroitin restore it, reducing pain and frequent urges in 60–70% of patients. For radiation and hemorrhagic cystitis, hyaluronate and heparin are administered, and for bacterial cystitis, antiseptics are administered. The drug is kept for 30–60 minutes; course weekly 6–8 times, then maintenance procedures once a month. The doctor selects the drug and regimen according to the diagnosis.
Why are instillations performed?
Instillation is the introduction of a drug directly into the bladder or urethra through a catheter, which creates a high local concentration without systemic action. It is used for chronic and interstitial cystitis, radiation cystitis, chronic urethritis (antiseptics, hyaluronic acid, heparin, drugs for mucosal restoration), as well as in oncourology - intravesical BCG and chemotherapy after TUR of a bladder tumor to prevent relapses.
How it goes
After treating the external opening of the urethra and introducing an anesthetic gel into the bladder, a thin catheter is inserted, residual urine is removed, 20–50 ml of solution is injected, and the catheter is removed. The drug is held for 30 minutes - 2 hours (with BCG - 2 hours, changing position). Course - from 6 to 10 procedures with an interval of 2 days to a week; oncology regimens - 6 weekly induction, then maintenance.
