Status and birth
For an IgG-positive mother with a history of relapses, suppressive prophylaxis is planned before delivery; seronegative - protection against infection in the third trimester (the most dangerous scenario is primary herpes before childbirth). Atypical complaints without rashes are also clarified by serology. Discordant couples are counseled about protection.
When is it appointed?
- pregnancy planning - TORCH status;
- pregnancy - screening and clarification of doubtful results;
- decision to vaccinate against rubella;
- lymphadenopathy, prolonged low-grade fever - etiology;
- clarification of the stage of infection (avidity).
Reading antibodies correctly
IgM is a marker of a fresh infection (but often “phonitis” is false), IgG is immune memory and protection. For pregnancy, the ideal profile is “IgG+, IgM−” (there is immunity, there is no risk); “IgG−, IgM−” means vulnerability (rubella - vaccination BEFORE conception!); “IgM+” requires clarification by IgG avidity: high avidity = long-standing infection, no danger. A competent interpretation saves you from unnecessary fears and interventions - the clinic doctor will analyze your profile.