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Mycoplasma and ureaplasma: when is it treated and when is it not?

Other names: Микоплазмоз, уреаплазмоз, Mycoplasma genitalium, Ureaplasma urealyticum, Mycoplasma hominis

Mycoplasma and ureaplasma are the topic around which the most confusion and unnecessary treatment has accumulated. Having discovered them in the analysis, many receive long courses of antibiotics, although not all of these microorganisms are causative agents of the disease. The key to understanding is simple: among them there is one unconditional pathogen that always requires treatment, and several representatives of opportunistic flora that are treated only under certain conditions.

🧾 МКБ-10: A63.8 🏥 Where it is treated: 2 M. genitalium - always treatUreaplasma - not alwaysLots of unnecessary treatment
👨‍⚕️ Which doctor
Urologist, venereologist, gynecologist
🔬 Diagnostics
PCR with species determination
💊 Treatment
Depends on the type and symptoms
📈 Prognosis
Favorable
⚠️ At risk
Unprotected contacts, change of partners
⏱ When to see a doctor
Scheduled appeal

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Выявлена Mycoplasma genitalium — лечение обязательно
  • Выделения и рези, не проходящие после лечения других инфекций
  • Боль внизу живота и температура у женщины
  • Отёк и боль в мошонке
  • Бесплодие и невынашивание беременности
  • Симптомы сохраняются после нескольких курсов антибиотиков

Who is who: the main difference

  • Mycoplasma genitalium is a recognized causative agent of sexually transmitted infections. Causes urethritis in men, inflammatory diseases of the pelvic organs in women. Always requires treatment, regardless of the presence of symptoms, and the partner is examined and treated
  • Ureaplasma urealyticum and Ureaplasma parvum are opportunistic microorganisms that are found in a significant proportion of healthy people without any symptoms. The mere fact of their detection is not a reason for treatment
  • Mycoplasma hominis - also refers to opportunistic flora; may be involved in the development of bacterial vaginosis and inflammatory processes, but does not always require treatment
Практический вывод, который экономит месяцы ненужного лечения: обнаружение уреаплазмы у человека без жалоб не означает, что нужно пить антибиотики. А вот Mycoplasma genitalium требует лечения в любом случае. Поэтому анализ должен определять конкретный вид, а не просто «микоплазмы и уреаплазмы».

When treatment is really needed

  • Mycoplasma genitalium detected - always, regardless of symptoms
  • There are symptoms of urethritis, cervicitis or inflammation, and other infections are excluded
  • Examination for infertility, when opportunistic flora is detected in a significant amount and there are signs of inflammation
  • Planning an intrauterine intervention or procedure during pregnancy
  • History of miscarriage - according to the decision of the gynecologist
  • Partner has a confirmed infection requiring treatment
  • Signs of inflammation in a smear and tests in the absence of other causes

When treatment is not usually needed

  • Ureaplasma or Mycoplasma hominis was discovered accidentally in a person without complaints
  • No signs of inflammation in the smear
  • The partner is healthy and no one has any complaints
  • The analysis was taken “for prevention” without indications
  • We are talking about a routine examination without pregnancy planning and interventions.

Unnecessary treatment in this situation is not harmless: it disrupts the microflora, increases the risk of fungal infections and intestinal disorders, creates bacterial resistance and creates in a person the feeling of a chronic disease where there is none.

Symptoms when they exist

  • In men: scanty discharge from the urethra, often in the morning
  • Burning and discomfort when urinating
  • Itching in the urethra
  • Discomfort in the perineum
  • Swelling and pain in the scrotum with involvement of the epididymis
  • In women: an increase in discharge, a change in its character
  • Discomfort during urination and sexual intercourse
  • Intermenstrual bleeding
  • Pain in the lower abdomen
  • Most often - complete absence of symptoms

Diagnostics

  • PCR with mandatory identification of a specific species is fundamentally important
  • Quantitative PCR for opportunistic flora
  • Smear microscopy - assessment of the presence of inflammation; this is a key guideline in treatment decisions
  • Examination for absolute pathogens: chlamydia, gonorrhea, trichomoniasis
  • Examination for syphilis, HIV, hepatitis
  • Examination by a urologist or gynecologist
  • Spermogram when planning pregnancy
  • Determination of sensitivity when treatment fails M. genitalium

Pay attention to the logic: not “if we find it, we treat it,” but “we find it, evaluate the type, the presence of inflammation and the clinical situation — and only then we decide.” It is this approach that distinguishes reasonable treatment from unnecessary treatment.

Treatment

  • For Mycoplasma genitalium - a specific regimen of antibacterial therapy; drugs are selected taking into account the growing resistance of this microorganism
  • Mandatory treatment of the partner if M. genitalium is detected
  • For conditionally pathogenic flora with signs of inflammation - a course of therapy as prescribed by a doctor
  • Sexual rest for the period of treatment
  • Control examination within the time limits established by the doctor
  • Restoration of microflora in women after the course
  • Treatment of concomitant bacterial vaginosis
  • Refusal to repeat courses “just in case” in the absence of indications
Mycoplasma genitalium заслуживает отдельного внимания: этот микроорганизм активно приобретает устойчивость к антибиотикам, во многом именно из-за бесконтрольного назначения препаратов при уреаплазме. Поэтому схему должен подбирать врач, а курс необходимо завершать полностью.

Where to get advice in Tashkent

A urologist or gynecologist will help you figure out whether your finding requires treatment by assessing the type of microorganism, the presence of inflammation and the clinical situation.

In Tashkent, such examination and consultation can be obtained at the UROLOGIC COMPLEX medical center and at the Tashkent Medical Park clinic.

If you have already been prescribed several courses of antibiotics “for ureaplasma” without lasting results, bring all previous tests to your appointment. It often turns out that no treatment was required at all, and the complaints have another reason. Clinic contacts are below.

Services and prices for this diagnosis

Based on official price lists of Tashkent clinics. The exact cost is determined after examination.

Frequently asked questions: Mycoplasmosis and ureaplasmosis

They found ureaplasma. Is it necessary to treat?+
Most often not. Ureaplasma belongs to the opportunistic flora and is found in a significant proportion of healthy people without any symptoms. Treatment is discussed in the presence of complaints and signs of inflammation, in case of infertility, miscarriage and before intrauterine interventions. Detection in itself in the analysis is not a reason for antibiotics.
How is Mycoplasma genitalium different from the rest?+
It is the only recognized causative agent of sexually transmitted infections in this group. It causes urethritis in men and inflammatory diseases of the pelvic organs in women; it always requires treatment, regardless of symptoms, and mandatory treatment of the partner. Therefore, the analysis must identify a specific species, and not just “mycoplasma”.
Why was I prescribed several courses, but nothing changed?+
A common situation. Possible reasons: treated opportunistic flora, which was not the cause of complaints; the true cause of the symptoms is different - for example, chronic pelvic pain syndrome, interstitial cystitis or a microflora disorder; or Mycoplasma genitalium was not detected. It makes more sense to reconsider the diagnosis than to prescribe another course.
Is ureaplasma sexually transmitted?+
It can be transmitted through sexual contact, but it is also present in people who do not have any problems. That is why its detection is not regarded as a diagnosis of “venereal disease” and does not require automatic treatment of both partners, unlike Mycoplasma genitalium.
Do I need to be examined before pregnancy?+
Screening for infections when planning pregnancy is advisable, but the scope is determined by the doctor. If Mycoplasma genitalium is detected, treatment is mandatory. When ureaplasma is detected, the decision is made taking into account the presence of inflammation, obstetric history and planned interventions - and not automatically.
Could this be the cause of infertility?+
Mycoplasma genitalium can cause pelvic inflammatory disease, which does affect fertility. The role of ureaplasma in infertility remains a matter of debate and is not considered proven in itself. In case of infertility, the examination should be comprehensive and not limited to the search for these microorganisms.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated mycoplasmosis and ureaplasmosis в Ташкенте

Главный вопрос при этих находках — нужно ли вообще лечение, и ответить на него может только врач, оценив вид микроорганизма, симптомы и ситуацию в целом. В Ташкенте такую консультацию и обследование можно получить в медицинском центре UROLOGIC COMPLEX и в clinicsе Tashkent Medical Park.

Tashkent, Uchtepa district, Chilanzar 12 apt., st. M. Shaykhzoda, 7
M Olmazor 🚶 1.2 km
M Chilonzor 🚶 1.7 km
M Mirzo Ulug'bek 🚶 2.5 km
🚌 Nearest bus stop 🚶 260 m · buses: 8, 41
Mon–Fri:08:30–17:00
Closed now
Tashkent, Учтепинский district, Chilonzor 12 block, st. М.Шайхзода, 7
M Olmazor 🚶 1.2 km
M Chilonzor 🚶 1.7 km
M Mirzo Ulug'bek 🚶 2.5 km
🚌 Nearest bus stop 🚶 310 m · buses: 8, 41
Mon–Fri:08:30–17:00
Closed now

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

Other diseases: Venereology

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