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Deficiency of B vitamins: symptoms, tests and how to compensate

Other names: Дефицит витаминов группы B, нехватка витамина B12, недостаток B1, дефицит B6, онемение при нехватке витаминов, витамины группы B симптомы

B vitamins are several different substances involved in energy metabolism, nervous system function, and hematopoiesis. The deficiency of each of them gives its own picture, but there is one thing in common: nerves and blood suffer. Lack of B12 and folate causes large red blood cell anemia, and B12 deficiency further damages nerve fibers, leading to numbness, tingling and unsteady gait. B1 deficiency is dangerous if you abuse alcohol and can seriously impair the functioning of your brain and heart. Deficiencies rarely arise out of nowhere: there is usually a reason - nutrition, intestinal disease, medications or alcohol, and this also needs to be found.

🧾 МКБ-10: E53.9 🏥 Where it is treated: 6 Nerves and blood sufferB12 can't be missedAlways looking for a reason
👨‍⚕️ Which doctor
Therapist, neurologist, gastroenterologist
🔬 Diagnostics
Complete blood count, vitamin B12, folic acid, B6, intestinal examination for malabsorption
💊 Treatment
Replenishment of deficiency in tablets or injections, nutrition correction, treatment of the cause
📈 Prognosis
Good with timely treatment; with advanced B12 deficiency, disturbances may remain
⚠️ At risk
Strict vegetarianism, stomach surgery, alcohol, intestinal diseases, taking metformin and heartburn medications
⏱ When to see a doctor
Planned; for neurological symptoms - urgent

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Онемение и покалывание в кистях и стопах, чувство ватных ног
  • Шаткость походки, особенно в темноте
  • Ухудшение памяти и спутанность сознания
  • Выраженная бледность и одышка при обычной нагрузке
  • Нарушение зрения или двоение
  • Спутанность и неустойчивость у человека, злоупотребляющего алкоголем

What vitamins are included in the group and what they are responsible for

Group B combines several independent vitamins: B1 is involved in obtaining energy from carbohydrates and is critical for nervous tissue, B2 and B3 ensure metabolism and the condition of the skin and mucous membranes, B6 is needed for the metabolism of amino acids and the synthesis of neurotransmitters, B9 and B12 are responsible for cell division and maturation of red blood cells, and B12 is also for the construction of the sheath of nerve fibers. The body does not store most of them for a long time, so intake must be regular. The exception is B12: its reserves in the liver last for years.

  • B1 - energy and work of the nervous system
  • B2 and B3 - metabolism, skin and mucous membranes
  • B6 - amino acid metabolism and neurotransmitters
  • B9 - cell division and fetal development
  • B12 - hematopoiesis and nerve sheath
  • B12 reserves are large, others are small

Who is more likely to have a deficiency?

The most vulnerable group for vitamin B12 are strict vegetarians and vegans, since it is found almost exclusively in animal products. Next come people after operations on the stomach and intestines, with atrophic gastritis, Crohn's disease and celiac disease, since absorption is impaired. Separately, long-term use of certain medications for heartburn and hypoglycemic agents is worthwhile. B1 deficiency is typical for alcohol abusers and prolonged vomiting. A lack of folic acid is typical during pregnancy and a poor diet without greens.

  • Strict vegetarians and vegans
  • Stomach and intestinal surgeries
  • Atrophic gastritis, celiac disease, Crohn's disease
  • Long-term use of heartburn medications and metformin
  • Alcohol abuse
  • Pregnancy and breastfeeding
  • Old age and monotonous diet

Symptoms

General manifestations are weakness, fatigue, irritability, loss of appetite. Changes in the mucous membranes are more recognizable: an inflamed, smooth tongue with a burning sensation, cracks in the corners of the mouth, and seizures. On the blood side, anemia with large red blood cells develops. The most important to recognize are the neurological symptoms of B12 deficiency: symmetrical numbness and tingling in the feet and hands, a feeling of wobbly legs, unsteadiness of gait, memory impairment. When B1 is deficient, people with alcohol dependence may experience confusion, impaired eye movements, and unsteadiness.

  • Weakness and fatigue
  • Burning and flattened tongue
  • Cracks in the corners of the mouth
  • Pallor and shortness of breath
  • Numbness and tingling in the arms and legs
  • Unsteadiness of gait and imbalance
  • Deterioration of memory and mood

Diagnostics

They start with a general blood test: an increased average volume of red blood cells indicates a deficiency of B12 or folic acid. Next, both vitamins are determined simultaneously, since their blood picture is the same, but the consequences of an error are different. Values ​​at the lower limit of normal with obvious symptoms do not exclude a deficiency, and the doctor can focus on additional indicators. If a deficiency is confirmed, they look for the cause: examine the stomach and intestines, clarify the diet and medications taken. In case of neurological complaints, a neurologist is involved.

  • Complete blood count with erythrocyte indices
  • Vitamin B12 and folic acid together
  • Vitamin B6 according to indications
  • Ferritin, as deficiencies often coexist
  • Gastroscopy and examination of the intestines for malabsorption
  • Assessing your medication and diet
  • Examination by a neurologist for numbness and unsteadiness

Treatment and nutrition

Replenishment is carried out in tablets or injections: the doctor chooses the method, focusing on the cause and severity. In case of impaired absorption and severe neurological symptoms, injections are preferred, followed by a transition to maintenance therapy. An important rule: if you suspect B12 deficiency, you should not start with folic acid alone - your blood count will improve, and nerve damage will continue unnoticed. At the same time, the diet is adjusted and the cause is treated. People on a strict plant-based diet need a B12 supplement constantly, not in courses.

  • B12 preparations in tablets or injections as prescribed by a doctor
  • Folic acid only after B12 testing
  • Thiamine for alcohol dependence and vomiting
  • Meat, fish, eggs, dairy products in the diet
  • Greens, legumes, grains as a source of folates
  • Continuous B12 Supplementation When Vegan
  • Treatment of bowel disease and review of medications
  • Control tests after the course

Services and prices for this diagnosis

Based on official price lists of Tashkent clinics. The exact cost is determined after examination.

Frequently asked questions: Vitamin B deficiency

Can you get enough B12 from plant foods?+
Practically none: this vitamin is found in animal products and specially enriched ones. Vegans and strict vegetarians need constant B12 supplementation and monitoring of levels by analysis, otherwise deficiency will develop over several years.
Are injections more effective than pills?+
In case of impaired absorption and severe neurological symptoms, injections are preferable. In other cases, high doses in tablets work comparable. The form and duration are selected by the doctor due to deficiency.
Will the numbness go away after treatment?+
If treatment is started early, symptoms usually go away within a few months. With prolonged deficiency, some of the disorders may persist, so it is impossible to postpone the examination if there is numbness and unsteadiness.
Is it true that metformin and heartburn medications reduce B12?+
Yes, long-term use of these groups of drugs is associated with a risk of deficiency. You cannot cancel them on your own: you need to discuss with your doctor periodic monitoring of B12 levels and, if necessary, supplementation.
Do B vitamins help everyone with fatigue?+
No. If there is no deficiency, the additional intake does not add energy. Fatigue is more often associated with iron deficiency, sleep disturbances, hypothyroidism or depression, and these reasons need to be addressed.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated B vitamin deficiency в Ташкенте

При онемении, жжении языка и слабости нужны осмотр терапевта и целенаправленные анализы. Clinics Ташкента с лабораторией и приёмом невролога:

Tashkent, Mirabad district, st. Oybek, 34d
M Toshkent 🚶 550 m
M Oybek 🚶 850 m
M Kosmonavtlar 🚶 1.3 km
🚌 Nearest bus stop 🚶 150 m · buses: 22
Tashkent, A-Yugnaki, st. Proyektnaya, G-40 landmark TTZ, market
🚌 Nearest bus stop 🚶 30 m · buses: 1, 17, 25
Mon–Fri:09:00–17:00
Closed now
Tashkent, Shaykhantaur district, st. Ankhor Buyi, 18d, Landmark: Tax office
M Mustaqillik maydoni 🚶 750 m
M Alisher Navoiy 🚶 850 m
M O'zbekiston 🚶 1.1 km
🚌 Nearest bus stop 🚶 260 m · buses: 28, 44, 46, 57
Mon–Fri:07:30–18:00
Closed now
Tashkent, Yunusabad district, st. Moykurgon
M Yunusobod 🚶 1.3 km
M Turkiston 🚶 1.3 km
M Shahriston 🚶 2.0 km
🚌 Nearest bus stop 🚶 70 m · buses: 43, 51
Mon–Fri:08:00–19:00
Closed now
st. Tadbirkor, house 76/1, Yakkasaray district, Tashkent Landmark: school No. 26
M Oybek 🚶 300 m
M Kosmonavtlar 🚶 450 m
M O'zbekiston 🚶 950 m
🚌 Nearest bus stop 🚶 160 m · buses: 57
Mon–Fri:09:00–17:00
Closed now
Tashkent, Almazar district, st. Usta Olim, 159d
M G'afur G'ulom 🚶 2.2 km
M Minor 🚶 2.3 km
M Abdulla Qodiriy 🚶 2.3 km
🚌 Nearest bus stop 🚶 190 m · buses: 5
Mon–Fri:09:00–17:00
Closed now

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

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