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Rheumatoid arthritis: symptoms and treatment in Tashkent

Other names: РА, серопозитивный ревматоидный артрит, ревматоидный полиартрит

Rheumatoid arthritis is a chronic autoimmune disease in which the immune system attacks the lining of the joints. Without treatment, inflammation destroys cartilage and bone, leading to permanent deformities and loss of hand function within a few years. The key concept of modern rheumatology is the “window of opportunity”: the first 3–6 months from the onset of symptoms, when basic therapy initiated can stop the disease and preserve joints. That is why, with morning stiffness and symmetrical swelling of the small joints of the hands, you cannot wait and be treated with ointments.

🧾 МКБ-10: M05 🏥 Where it is treated: 6 Window of opportunity – 3–6 monthsStiffness for more than an hourMethotrexate is the basic drug
👨‍⚕️ Which doctor
Rheumatologist
🔬 Diagnostics
RF, ACCP, ESR, CRP, ultrasound and x-ray of joints
💊 Treatment
Methotrexate and other basic drugs, biological therapy
📈 Prognosis
Remission is achievable with early treatment
⚠️ At risk
Female gender, smoking, heredity
⏱ When to see a doctor
Contact us in the first weeks

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Отёк и боль в мелких суставах кистей более 6 недель
  • Утренняя скованность дольше часа
  • Высокая температура и резкая боль в одном суставе — исключить инфекцию
  • Одышка и сухой кашель — возможно поражение лёгких
  • Онемение и слабость в кистях
  • Быстрое появление деформаций пальцев

How to recognize

  • Symmetrical damage: the joints of the same name on both hands are affected
  • Most often the small joints of the hands (metacarpophalangeal and proximal interphalangeal) and feet are involved.
  • Morning stiffness lasting longer than 30–60 minutes is a key sign; with arthrosis it is shorter
  • Swelling, spindle fingers, pain when shaking hands and squeezing the hand
  • Common symptoms: fatigue, low-grade fever, weight loss
  • The distal interphalangeal joints (near the nails) are usually NOT affected - this distinguishes RA from psoriatic arthritis and arthrosis
Отличие от артроза простое: при артрозе боль усиливается к вечеру и после нагрузки, скованность короткая; при ревматоидном артрите хуже всего утром, скованность длится час и более, а движение приносит облегчение.

Survey

  1. Ревматоидный фактор (РФ) — повышен примерно у 70% пациентов, но встречается и у здоровых.
  2. АЦЦП (антитела к циклическому цитруллинированному пептиду) — значительно более специфичный тест, может быть положительным задолго до появления симптомов.
  3. СОЭ и С-реактивный белок — оценка активности воспаления.
  4. УЗИ суставов с допплером — выявляет синовит на самой ранней стадии, когда рентген ещё нормальный.
  5. Рентген кистей и стоп — эрозии появляются позже, служат для оценки прогрессирования.
  6. Общий анализ крови, печёночные и почечные показатели — перед началом терапии.

Treatment

The goal of modern therapy is not to “relieve pain,” but to achieve remission, that is, the complete absence of active inflammation. The strategy is called “treat to goal.”

  • Methotrexate is the basic first-line drug; taken once a week, always together with folic acid on other days
  • Other basic drugs - in case of intolerance or insufficient effect
  • Biological and targeted therapy - if basic drugs are ineffective
  • Glucocorticosteroids - in a short course as a “bridge” before the onset of basic therapy, and not as a permanent treatment
  • NSAIDs - for symptom relief only; they do not stop joint destruction
  • Regular monitoring of blood tests during therapy
  • Physical therapy, maintaining mobility, orthoses if necessary
Метотрексат при ревматоидном артрите принимают ОДИН РАЗ В НЕДЕЛЮ. Ежедневный приём по ошибке — опасная и, к сожалению, встречающаяся ситуация, приводящая к тяжёлым осложнениям.

What is important for the patient to know

  • Smoking cessation is mandatory: smoking both causes RA and reduces the effectiveness of treatment
  • Rheumatoid arthritis increases cardiovascular risk - blood pressure and lipids need to be controlled
  • Before starting therapy, tuberculosis and hepatitis are checked
  • Vaccination against influenza and pneumococcus is recommended; live vaccines are contraindicated during therapy
  • Pregnancy is planned in advance: some medications must be discontinued at a certain time
  • Regular, feasible physical activity preserves joint function
  • For any infection during therapy, you should contact your doctor.

Frequently asked questions: Rheumatoid arthritis

How is it different from arthrosis?+
With arthrosis, the pain intensifies in the evening and after exercise, and the stiffness is short-lived. Rheumatoid arthritis is worst in the morning, the stiffness lasts an hour or more, the lesions are symmetrical, and movement brings relief.
What is a “window of opportunity”?+
This is the first 3–6 months from the onset of symptoms, when basic therapy initiated can stop the disease and prevent joint destruction. Later, treatment options are significantly reduced.
The rheumatoid factor is negative, which means it’s not arthritis?+
No. About a third of patients are rheumatoid factor negative. ACCP is more specific, and the diagnosis is made based on a combination of clinical findings, tests, and ultrasound or x-ray data.
How is methotrexate taken?+
Once a week, on the same day, always with folic acid on other days. Taking it daily by mistake is extremely dangerous.
Can I get by with painkillers?+
No. NSAIDs relieve pain but do not stop joint destruction. Without basic therapy, the disease progresses and leads to deformities.
Is it possible to plan a pregnancy?+
Yes, but in advance and together with a rheumatologist: some medications must be stopped a certain period before conception, and some are compatible with pregnancy.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated rheumatoid arthritis в Ташкенте

При ревматоидном артрите результат напрямую зависит от того, насколько рано начата базисная терапия. Приём ревматологов в Ташкенте:

Tashkent, Mirabad district, st. Oybek, 34d
M Toshkent 🚶 550 m
M Oybek 🚶 850 m
M Kosmonavtlar 🚶 1.3 km
🚌 Nearest bus stop 🚶 150 m · buses: 22
Tashkent, Chilanzar district, 19-kv, 65d
M Olmazor 🚶 1.5 km
M Chilonzor 🚶 2.4 km
M Mirzo Ulug'bek 🚶 3.4 km
🚌 Nearest bus stop 🚶 260 m · buses: 48
Mon–Fri:08:00–17:00
Open now
Tashkent city, Shaykhantakhur district, st. Bogkucha, 20d
M Tinchlik 🚶 900 m
M Chorsu 🚶 1.2 km
M G'afur G'ulom 🚶 2.1 km
🚌 Nearest bus stop 🚶 130 m · buses: 5, 11, 23, 28, 29
Mon–Fri:09:00–17:00
Open now
E

Eurosun Healthcare

Private · Shaykhantakhur district

st. Alisher Navoiy 10, Shaykhantakhur district, Tashkent Landmarks: opposite the Trustbank...
🚌 Nearest bus stop 🚶 130 m
Пн–Sat:08:00–18:00
Open now
Bogkucha block, st. Bogkucha, house 20, Shaykhantakhur district, Tashkent Landmark: childr...
M Chorsu 🚶 1.1 km
M Tinchlik 🚶 1.1 km
M G'afur G'ulom 🚶 2.0 km
🚌 Nearest bus stop 🚶 320 m · buses: 5, 11, 23, 28, 29
Mon–Fri:00:00–24:00
Open now
M

MEDANIS

Медицинский центр · Mirzo-Ulugbek district

"ул. Buyuk Ipak Yo'li, 103, Mirzo-Ulugbek district, Ташкент"
M Buyuk Ipak Yo'li 🚶 800 m
M Pushkin 🚶 850 m
M Hamid Olimjon 🚶 1.8 km
🚌 Nearest bus stop 🚶 90 m · buses: 1, 24

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

Other diseases: Rheumatology

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