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Postthrombotic disease: swelling of the leg after thrombosis and its treatment

Other names: Посттромботическая болезнь, посттромбофлебитический синдром, ПТФС, отёк ноги после тромбоза, последствия тромбоза глубоких вен, трофическая язва после тромбоза

Postthrombotic disease is a chronic condition that develops after deep vein thrombosis. The thrombus partially resolves over time, but the wall of the vein and its valves remain damaged: the blood begins to flow in the opposite direction and stagnates in the tissues of the lower leg. Because of this, the leg swells, becomes heavier in the evening, the skin darkens and thickens, and in advanced cases, a trophic ulcer forms. The problem develops gradually, sometimes years after thrombosis, and its severity directly depends on whether the person wears compression hosiery and whether it is observed by a doctor. It is impossible to completely restore the valves, but it is quite possible to slow down the disease.

🧾 МКБ-10: I87.0 🏥 Where it is treated: 6 Consequence of vein thrombosisThe basis of treatment is compressionRisk of trophic ulcer
👨‍⚕️ Which doctor
Phlebologist, vascular surgeon
🔬 Diagnostics
Ultrasound examination of veins with Dopplerography, coagulogram, examination of the skin of the lower leg
💊 Treatment
Compression hosiery, movement mode, skin care, according to intervention indications
📈 Prognosis
Chronic course, but with regular compression the ulcer can usually be avoided
⚠️ At risk
Previous thrombosis, obesity, standing work, repeated thrombosis, refusal of compression
⏱ When to see a doctor
Planned; with sudden swelling and shortness of breath - 103

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Внезапная одышка и боль в груди — возможна тромбоэмболия, звоните 103
  • Резкое нарастание отёка и боли в ноге за несколько часов
  • Нога стала горячей, багрово-синюшной, кожа натянута
  • Язва увеличивается, появились гной и неприятный запах
  • Высокая температура с ознобом и покраснением голени
  • Онемение, похолодание стопы, невозможность наступить на ногу

Why does the disease develop?

The deep veins of the legs have valves that allow blood to flow only upward to the heart. The thrombus damages them and the vein wall itself. Even after successful dissolution of the thrombus, the valves often remain incompetent, and the lumen of the vein remains partially narrowed by scars. When walking, the blood rises worse, some of it returns down, the pressure in the veins of the lower leg increases. Fluid and blood cells leak into the tissues, chronic inflammation develops, and the skin becomes thinner and darker. The higher the level of thrombosis and the longer it was not treated, the more severe the consequences.

  • Damage to venous valves by thrombus
  • Scar narrowing of the vein lumen
  • Reverse blood flow and venous stasis
  • Increased pressure in the veins of the leg
  • Chronic inflammation and skin changes

Symptoms

The first complaints appear gradually: by the end of the day, the leg feels heavy, the shoes become tight, and marks remain from the elastic of the sock. The swelling first goes away overnight, then becomes permanent. Bursting pain, night cramps in the calves, and itching occur. The skin of the lower third of the leg acquires a brownish tint, becomes dense, and the hair on it falls out. Against this background, even a small scratch can turn into a long-lasting ulcer, usually above the inner ankle.

  • Swelling of the lower leg, worsening in the evening
  • Heaviness and swelling in the leg
  • Night cramps, itchy skin
  • Brown pigmentation in the lower third of the leg
  • Thickening of the skin and subcutaneous tissue
  • Dilated saphenous veins
  • Trophic ulcer above the ankle

Diagnostics

The main method is ultrasound examination of veins with Dopplerography. It shows whether there are residual thrombotic masses, how much the lumen of the vein has been restored, whether the valves are working and whether there is reverse blood flow. The doctor examines the skin, measures the circumference of both legs and assesses the degree of changes according to the international classification. In case of repeated thrombosis, thrombosis at a young age or unusual location, the coagulation system is additionally examined. In case of an ulcer, a culture of the discharge is taken and the arterial blood flow is assessed, since compression is not acceptable in all conditions.

  • Ultrasound of the veins of the lower extremities with Dopplerography
  • Dynamic calf circumference measurement
  • Skin and ulcer assessment
  • Coagulogram, examination for thrombophilia according to indications
  • Assessment of arterial blood flow before compression
  • Sowing of discharge from an ulcer during suppuration

Treatment

The basis of treatment is constant compression: knitwear or bandage that is correctly selected in size and grade, which is put on in the morning, without getting out of bed, and worn all day. This is not an auxiliary measure, but the main method to reduce swelling and prevent ulcers. The second support is movement: walking, ankle exercises, raising legs in a lying position. Phlebotropic drugs reduce heaviness and swelling, but do not replace compression; Anticoagulants are continued strictly as prescribed by the doctor. Ulcers require regular care and dressings under the supervision of a specialist. In some cases, endovascular interventions on narrowed veins are discussed.

  • Everyday compression hosiery of the right grade
  • Regular walking and calf exercises
  • Elevated leg position while resting
  • Skin care: hydration, protection from injury
  • Phlebotropic drugs prescribed by a doctor
  • Continuation of anticoagulants according to the doctor’s regimen
  • Dressings and treatment of ulcers by a specialist
  • Losing weight, avoiding standing for long periods of time

Prevention of complications

The main task is to prevent recurrent thrombosis and trophic ulcers. Repeated thrombosis sharply worsens the condition of the veins, so it is important to follow recommendations on anticoagulants, prevention during long flights and after operations, and weight control. The skin of the lower leg should be protected: avoid hot baths and saunas, do not comb, do not use aggressive products, treat small wounds in a timely manner. At the first signs of skin inflammation or a non-healing wound, you should see a doctor and not be treated with homemade compresses.

  • Do not stop anticoagulants yourself
  • Compression on long trips and flights
  • Warm up your legs during sedentary work every hour
  • Avoidance of saunas and hot baths
  • Daily moisturizing of the skin of the legs
  • Comfortable shoes without putting pressure on the foot
  • Immediate visit to the doctor if a wound does not heal

Services and prices for this diagnosis

Based on official price lists of Tashkent clinics. The exact cost is determined after examination.

💊 Treatment

Frequently asked questions: Postthrombotic disease

How long to wear compression stockings?+
In case of post-thrombotic disease, compression is needed constantly, throughout the day, and not in courses. The product loses its elasticity after about six months of regular wear, so it is changed periodically. The class and size are selected by the doctor after examination and measurements.
Is it possible to cure post-thrombotic disease completely?+
It is impossible to restore damaged vein valves, so the condition is considered chronic. However, with constant compression, movement and skin care, it is possible to reduce swelling, avoid ulcers and maintain normal activity.
Do ointments and gels help?+
Local remedies may provide some relief from heaviness and itching, but they do not affect venous pressure. They cannot be considered the main treatment: without compression and movement, the disease will continue to progress.
Is it possible to warm your leg and go to the bathhouse?+
Thermal procedures dilate veins and increase swelling, so saunas, hot baths and heating pads are not recommended. A cool shower on the shins, elevated position of the legs and therapeutic walking are more beneficial.
How to understand that repeated thrombosis has begun?+
The rapid increase in swelling and pain over hours or days is alarming, especially with a feeling of fullness and blueness. If you experience shortness of breath, chest pain or coughing up blood, you should immediately call 103.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated postthrombotic disease в Ташкенте

Определить степень повреждения вен и подобрать правильный класс компрессии можно только после ультразвукового исследования. Clinics Ташкента с флебологами и УЗИ сосудов:

Tashkent, Mirabad district, st. Oybek, 34d
M Toshkent 🚶 550 m
M Oybek 🚶 850 m
M Kosmonavtlar 🚶 1.3 km
🚌 Nearest bus stop 🚶 150 m · buses: 22
Tashkent, Olmazar Tumani, Kichik Khalka Yuli 5 "A" y
M Beruniy 🚶 500 m
M Tinchlik 🚶 1.1 km
M Chorsu 🚶 2.9 km
🚌 Nearest bus stop 🚶 190 m · buses: 31, 34
Mon–Fri:08:30–17:00
Closed now
P

Phlebo Service

Private · Yakkasaray district

Sharshara passage, 114, Yakkasaray district, Tashkent Landmarks: shopping center "Next" ("...
M Mustaqillik maydoni 🚶 1.5 km
M Paxtakor 🚶 1.5 km
M Xalqlar Do'stligi 🚶 1.6 km
🚌 Nearest bus stop 🚶 370 m · buses: 11, 32, 47
Пн–Sat:10:00–18:00
Closed now
Tashkent, Yakkasaray district, st. Кичик халка йули, 70А
M Choshtepa 🚶 2.5 km
M O'zgarish 🚶 3.2 km
M Chinor 🚶 3.3 km
🚌 Nearest bus stop 🚶 370 m · buses:
Mon–Fri:00:00–24:00
Closed now
ул.Шифокорлар, 8/1
M Beruniy 🚶 2.4 km
M Tinchlik 🚶 3.8 km
🚌 Nearest bus stop 🚶 450 m · buses: 31
"ул. Чингиза Айтматова, 38, Yunusabad district, Ташкент"
M Minor 🚶 950 m
M Abdulla Qodiriy 🚶 1.2 km
M Bodomzor 🚶 1.3 km
🚌 Nearest bus stop 🚶 150 m · buses: 38

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

Other diseases: Phlebology

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