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Prurigo (prurigo): itchy nodules on the skin and how to break the cycle of itching

Other names: Почесуха, пруриго, узловатая почесуха, зудящие узелки на коже, пруриго Гебры, сильный зуд с расчёсами

Prurigo, or prurigo, is a chronic skin disease in which dense, highly itchy nodules and nodes appear, most often on the extensor surfaces of the arms and legs, on the back and abdomen. The main feature is that the disease maintains itself: itching forces you to scratch the skin, scratching damages the nerve endings and intensifies the itching, and new dense elements form at the site of scratching. Prurigo can occur against the background of atopic dermatitis, as well as with internal diseases - liver and kidney diseases, diabetes, thyroid disorders, iron deficiency, and less often with blood diseases. Therefore, treatment always includes searching for the cause.

🧾 МКБ-10: L28.2 🏥 Where it is treated: 6 Vicious circle of itchingThere is often an underlying illnessNeed to find a reason
👨‍⚕️ Which doctor
Dermatologist, allergist, and, if necessary, therapist and neurologist
🔬 Diagnostics
General and biochemical blood test, glucose, TSH, ferritin, examination for parasites, if indicated - skin biopsy
💊 Treatment
Treatment of the underlying cause, topical anti-inflammatory therapy, anti-itch medications, skin care
📈 Prognosis
The course is chronic, but with proper treatment the itching is controlled
⚠️ At risk
Atopic dermatitis, dry skin, liver and kidney diseases, diabetes, stress, insect bites
⏱ When to see a doctor
Planned

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Зуд по всему телу с похудением, ночной потливостью и увеличением лимфоузлов
  • Пожелтение кожи и склер, тёмная моча
  • Зуд у беременной женщины, особенно на ладонях и стопах
  • Высокая температура и гнойное отделяемое of расчёсов
  • Резкое появление зуда после начала нового лекарства
  • Бессонница и подавленность из-за постоянного зуда

What does prurigo look like?

The elements are dense nodules ranging in size from a few millimeters to one and a half to two centimeters, the skin over them is often thickened, with a crust or abrasion in the center from scratching. The color varies from pink to dark brown, especially in people with dark skin. The rashes are located symmetrically where it is easy to reach with your hand, and typically spare the central part of the back, which a person cannot comb. Over time, the skin between the nodules becomes rougher, the skin pattern intensifies, and dark spots and scars remain.

  • Dense knots with combed tops
  • Symmetrical arrangement on arms, legs, back
  • The out-of-reach area on the back remains clear
  • Thickening of the skin between the elements
  • Dark spots and scars after healing
  • Severe itching, worse in the evening

Reasons and what to look for

Prurigo is not a final diagnosis, but a signal to look for the source of the itching. In some patients, this is a manifestation of atopic dermatitis or severe dry skin. For others, internal diseases are behind the itching: chronic kidney disease, liver disease with bile stagnation, diabetes mellitus, thyroid disorders, iron deficiency, and, less commonly, lymphoma and other blood diseases. Nervous factors play a role: nerve damage from diabetes and shingles, as well as chronic stress and anxiety. Sometimes the trigger is insect bites or scabies.

  • Atopic dermatitis and dry skin
  • Chronic kidney disease
  • Diseases of the liver and biliary tract
  • Diabetes mellitus
  • Thyroid dysfunction
  • Iron deficiency
  • Parasitosis and scabies
  • Side effects of drugs

Survey

The diagnosis of prurigo itself is made upon examination by the characteristic appearance of the elements. Most of the time is spent searching for the cause of the itching. The standard set includes a general blood test, biochemistry with liver and kidney parameters, glucose, TSH and ferritin. If parasites are suspected, appropriate tests are prescribed; if scabies is suspected, an examination with a search for burrows is prescribed. If the rash is atypical or does not respond to treatment, a skin biopsy is performed. In older people with itching all over the body, the doctor must rule out blood diseases.

  • General blood test
  • Biochemistry: liver function tests, creatinine
  • Blood glucose and glycated hemoglobin
  • TSH
  • Ferritin
  • Examination for parasites
  • Skin biopsy for an atypical picture

How to break the cycle of itching

While a person is scratching his skin, no treatment will give a lasting result. Therefore, the practical part is important: short-cut nails, cotton gloves at night, cool showers instead of hot ones, avoidance of hard washcloths and aggressive soaps. Applying liberal amounts of emollients several times a day reduces dryness and itching. Cooling compresses and menthol products prescribed by a doctor help. It is worth removing provocateurs: overheating, woolen fabrics on a naked body, alcohol and spicy foods if you are prone to hot flashes.

  • Short nails, gloves at night
  • Cool short shower, gentle cleansing
  • Emollients 2–3 times daily
  • Cooling compresses
  • Cotton loose clothing
  • Stress control, if necessary, help from a psychologist

Treatment

The treatment is selected by a dermatologist, and it is always two-component: an effect on the skin and correction of the underlying cause. External anti-inflammatory agents are used on the skin, including a course of topical glucocorticoids and calcineurin inhibitors, sometimes under an occlusive dressing for dense nodes. For common forms, phototherapy is used. The doctor may prescribe systemic drugs that affect the transmission of the itching signal, and in case of severe persistent disease, modern immunobiological drugs. Antihistamines do not help everyone, since itching with prurigo is associated not only with histamine.

  • External glucocorticoids in a course as prescribed by a doctor
  • Calcineurin inhibitors
  • Phototherapy
  • Systemic medications to control itching
  • Treatment of the underlying disease
  • Treatment of infected scratches
  • Refusal of independent long-term use of hormonal ointments

Services and prices for this diagnosis

Based on official price lists of Tashkent clinics. The exact cost is determined after examination.

Frequently asked questions: Prurigo (prurigo)

Is pruritus contagious?+
No, prurigo is not spread from person to person. But similar itchy rashes are caused by scabies, which is contagious and requires treatment for all family members. Therefore, if itchy nodules appear, especially with increased itching at night, you need to be examined by a dermatologist.
Why don't antihistamines help?+
In prurigo, itching is maintained not only by the release of histamine, but also by changes in the nerve fibers of the skin and in signal transmission. Therefore, conventional antiallergic drugs have a weak effect, and the doctor selects drugs with a different mechanism of action.
Will prurigo go away on its own?+
Sometimes the rashes subside after the cause is eliminated - for example, after treating iron deficiency or normalizing thyroid function. But more often, without treatment, the disease drags on for months and years, since scratching itself supports the process.
Is it possible to use hormonal ointment for a long time?+
There is no doctor's supervision. External glucocorticoids are effective, but with prolonged uncontrolled use they thin the skin and cause other side effects. The dermatologist selects the strength of the drug, the duration of the course and the reduction scheme.
Does stress affect itching?+
Yes. Anxiety and disturbed sleep reduce the threshold for the perception of itching, and the habit of scratching the skin is reinforced as an automatic action. Managing stress and restoring sleep is an important part of treatment, not an addition to it.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated pruritus в Ташкенте

Разобраться в причине зуда и подобрать лечение поможет дерматолог. Clinics Ташкента с дерматологами:

Tashkent, Mirabad district, st. Oybek, 34d
M Toshkent 🚶 550 m
M Oybek 🚶 850 m
M Kosmonavtlar 🚶 1.3 km
🚌 Nearest bus stop 🚶 150 m · buses: 22
Tashkent, Shaikhantaur district, 10d. Landmark: Labzak
M Minor 🚶 900 m
M Bodomzor 🚶 1.0 km
M Abdulla Qodiriy 🚶 1.3 km
🚌 Nearest bus stop 🚶 320 m · buses: 35
Mon–Fri:09:00–17:00
Closed now
Tashkent, Olmazar Tumani, Kichik Khalka Yuli 5 "A" y
M Beruniy 🚶 500 m
M Tinchlik 🚶 1.1 km
M Chorsu 🚶 2.9 km
🚌 Nearest bus stop 🚶 190 m · buses: 31, 34
Mon–Fri:08:30–17:00
Closed now
Zulfiyahonim st., 18
M Alisher Navoiy 🚶 1.1 km
M G'afur G'ulom 🚶 1.3 km
M Abdulla Qodiriy 🚶 1.7 km
🚌 Nearest bus stop 🚶 90 m · buses: 35
Пн–Sat:00:00–24:00
Open now
st. Buyuk Ipak Yuli, building 131A, Mirzo-Ulugbek district, Tashkent Landmarks: carpet sto...
M Buyuk Ipak Yo'li 🚶 200 m
M Pushkin 🚶 1.8 km
M Hamid Olimjon 🚶 2.8 km
🚌 Nearest bus stop 🚶 70 m · buses: 1, 24
Mon–Fri:09:00–17:00
Closed now
Tashkent, Mirabad district, st. Nukussky, 14d
M Choshtepa 🚶 2.8 km
M O'zgarish 🚶 3.2 km
M Oybek 🚶 3.6 km
🚌 Nearest bus stop 🚶 280 m · buses: 9Т, 12
Mon–Fri:09:00–17:00
Closed now

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

Other diseases: Dermatology

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