What forms are there?
Several conditions with different prognosis are combined under one name. Small plaque parapsoriasis manifests itself as oval spots up to five centimeters in diameter, often stretched along the lines of the skin on the sides and trunk; The current is calm. The large plaque form produces lesions of more than five centimeters, often in areas protected from the sun, with uneven edges and areas of thinning of the skin - it is this that requires careful observation. Separately, acute and chronic lichenoid parapsoriasis are distinguished, in which the rashes look like nodules and crusts.
- Small plaque: spots up to five centimeters, benign course
- Large plaque: large lesions, risk of progression to skin lymphoma
- Poikilodermic variant: variegation, spider veins, atrophy
- Chronic lichenoid: small nodules with scales
- Acute lichenoid: rash with crusts and healing with scars
Causes and what is known about the mechanism
The exact reason is unknown. It is believed that a cluster of T-lymphocytes forms in the skin, which persists for a long time and maintains low-grade inflammation. The role of previous infections, reactions to medications and characteristics of the immune system are discussed, but no single factor is recognized as the main one. Parapsoriasis is not related to diet, hygiene or nervous tension, although stress can aggravate any skin complaints. Hereditary transmission is not typical, familial cases are rare.
- Long-term activation of T-lymphocytes in the skin
- Previous infections as a possible trigger factor
- Reactions to certain medications
- Not contagious and not transmitted through household contact
- Not related to diet and hygiene
Symptoms
The main symptom is persistent patches of pink, reddish-brown or yellowish hue with fine scaling, which is sometimes compared to tissue paper. They exist for months and years, sometimes fading, sometimes becoming more noticeable, often improving in the summer. Unlike psoriasis, the scales are not silvery and do not scrape off in layers, and when scraped, drops of blood do not appear. General health does not suffer, there is no fever or weakness.
- Spots with thin peeling on the trunk, sides, thighs
- No or mild itching
- The lesions persist for months without sudden exacerbations
- Better in summer, worse in winter
- In the large plaque form - thinning and variegation of the skin
Diagnostics
Examination is not enough: similar spots are caused by psoriasis, eczema, pityriasis rosea, fungal infections and seborrheic dermatitis. The doctor evaluates the shape, location and boundaries of the lesions, performs dermatoscopy, and takes scrapings for fungi. The key method is skin biopsy with histological and, if necessary, immunohistochemical examination. In the large plaque form, the biopsy is sometimes repeated after some time from different foci, because early changes in skin lymphoma may not appear immediately. Blood tests can help rule out underlying problems.
- Examination and dermatoscopy
- Scraping for pathogenic fungi
- Skin biopsy with histology
- Immunohistochemistry and clonality studies for suspected lymphoma
- General blood test with leukemia formula
- Repeated biopsies if the picture changes
Treatment and observation
The goal of treatment is to reduce peeling and cosmetic defects, and in the case of large-plaque forms, to notice changes in time. The doctor usually starts with emollients and topical glucocorticoids in short courses. Phototherapy with narrow-band ultraviolet light helps, and natural sun in moderation often improves skin condition. You should not expect a complete cure: the disease is chronic, but in the small plaque form it is not dangerous. Regular examinations by a dermatologist are a mandatory part of the plan; the schedule and frequency are determined by the doctor.
- Daily use of emollients
- External glucocorticoids in courses as prescribed by a doctor
- Narrowband ultraviolet phototherapy
- Moderate sun exposure without burns
- Routine examinations and photographic recording of lesions
- Repeat biopsy if the appearance of the spots changes