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Retinopathy of prematurity: timing of examination and treatment

Other names: Ретинопатия недоношенных, РН у младенцев, disease сетчатки у недоношенного ребёнка, осмотр глаз недоношенного, отслойка сетчатки у новорождённого

The retinal vessels grow from the center to the periphery and complete their path only towards the end of pregnancy. In case of premature birth, this process is interrupted: the retina at the edge remains without blood vessels, experiences a lack of oxygen and, in response, triggers the growth of defective new vessels. They are fragile, bleed and drag along scar tissue, which can detach the retina. This is retinopathy of prematurity - one of the leading causes of childhood blindness, completely preventable with timely examination. Externally, the child’s eyes look absolutely normal, and it is impossible to notice the disease without a special examination.

🧾 МКБ-10: H35.1 🏥 Where it is treated: 7 No external signsTiming inspection is requiredEarly treatment saves vision
👨‍⚕️ Which doctor
Ophthalmologist, neonatologist, pediatrician
🔬 Diagnostics
Examination of the fundus with pupil dilation through a special lens, retinal camera, ultrasound of the eye
💊 Treatment
Observation for mild stages, laser coagulation, injections of drugs into the eye, for detachment - surgery
📈 Prognosis
Good if treated early; later stages lead to low vision and blindness
⚠️ At risk
Short gestation and low birth weight, long-term oxygen support, sepsis, blood transfusions
⏱ When to see a doctor
Urgent - according to the established inspection schedule, without delay

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Первый осмотр глазного дна до сих пор не проведён
  • Пропущен назначенный офтальмологом контрольный осмотр
  • Белый или сероватый зрачок
  • Ребёнок не следит взглядом за лицом и игрушкой в положенном возрасте
  • Глаза начали отклоняться в стороны, появилось косоглазие
  • Постоянные непроизвольные движения глаз

What happens to the retina

By the time of normal birth, the vessels have time to grow to the edge of the retina. If a baby is born prematurely, growth stops and a zone without blood supply remains. This zone secretes substances that stimulate vascular formation, and a shaft with irregular vessels growing from it appears at the border with the normal retina. The process either spontaneously fades, and the retina gradually matures, or progresses. In the worst case scenario, the growing fibrous tissue contracts and tears the retina away from the underlying layers.

  • Stage 1 - thin demarcation line at the border of zones
  • Stage 2 - the line turns into a towering shaft
  • Stage 3 - growth of newly formed vessels into the vitreous body
  • Stage 4 - partial retinal detachment
  • Stage 5 - complete retinal detachment
  • Separately, an aggressive rear form with a fast flow is distinguished

Who's at risk

The main factors are the degree of prematurity and birth weight: the lower the term and weight, the higher the likelihood. Long-term oxygen support with fluctuations in oxygen concentration plays a role, so in modern departments it is carefully dosed and controlled. The risk is increased by severe neonatal periods: sepsis, intraventricular hemorrhages, anemia and blood transfusions, prolonged artificial ventilation, intrauterine growth retardation and multiple pregnancies.

  • Gestational age less than 32 weeks
  • Birth weight less than 1500 grams
  • Long-term oxygen therapy and mechanical ventilation
  • Sepsis and severe infections
  • Blood transfusions, severe anemia
  • Multiple pregnancy, fetal growth restriction

Inspection timing is the most important

Retinopathy develops asymptomatically, and the only protection is a routine examination of the fundus within a strictly defined time frame. The first examination of a premature baby is usually prescribed a few weeks after birth; the exact date is determined by an ophthalmologist based on the gestational age and condition of the child. Further examinations are repeated every one to two weeks, and more often if the picture is alarming, until the vessels grow to the edge of the retina. Missing even one visit is dangerous: the disease can progress to a severe stage in a matter of days, and treatment is effective only in a narrow time window.

  • The first examination is prescribed by an ophthalmologist together with a neonatologist
  • The examination is carried out with pupil dilation through a special lens.
  • Repeat examinations every one to two weeks
  • Observation continues until the retinal vessels mature completely.
  • A missed visit can cost your child his sight.
  • Examinations are not a substitute for assessing the child’s behavior and reactions.

How a child is examined

Before the examination, drops that dilate the pupil and anesthetic drops are instilled. The doctor uses a forehead ophthalmoscope and a special lens, and holds the eyelids with a soft speculum. The procedure takes several minutes and is unpleasant for the child, but not dangerous; Many departments use wide-field retinal cameras, which record the picture of the fundus in the form of an image and allow it to be compared over time. The doctor describes the affected area, stage and presence of signs of vascular activity - the decision on treatment directly depends on this.

  • Pupil dilation with drops before examination
  • Examination of the fundus through a lens with an eyelid speculum
  • Photographic recording with a retinal camera
  • Assessment of the zone, stage and activity of the process
  • Ultrasound of the eye in opaque media
  • Control examinations according to the schedule established by the doctor

Treatment and follow-up

Mild stages often regress on their own, and observation is sufficient. When the threshold stage is reached, treatment is carried out urgently, usually within the next few days: laser coagulation of the avascular zone of the retina is performed or a drug is injected into the eye cavity that suppresses the growth of new vessels. Retinal detachment requires complex surgery and the outcome is no longer guaranteed. Even after successful treatment, the child remains under the supervision of an ophthalmologist for years: such children more often develop myopia, strabismus, amblyopia and glaucoma, which need to be corrected in time.

  • Observation for stages 1–2 without signs of progression
  • Laser coagulation of the retina at the threshold stage
  • Intravitreal administration of the drug according to indications
  • Surgery for retinal detachment
  • Annual follow-up with an ophthalmologist in the future
  • Timely correction of myopia, strabismus, amblyopia

Services and prices for this diagnosis

Based on official price lists of Tashkent clinics. The exact cost is determined after examination.

Frequently asked questions: Retinopathy of prematurity

When is the first eye examination of a premature baby necessary?+
The timing is determined by the ophthalmologist together with the neonatologist, based on gestational age and birth weight; This is usually a few weeks after giving birth. It is important not to wait for discharge and complaints: the appointed date must be strictly observed.
Can a disease be detected by a child’s behavior?+
No. At the stages when treatment is most effective, the eyes look normal and the child behaves as usual. External signs - squint, lack of tracking, white pupil - appear already in severe stages.
Does the child feel pain during the examination?+
The examination is unpleasant: the pupil is dilated with drops, the eyelids are held in place with a dilator. Anesthetic drops reduce discomfort, the procedure lasts several minutes and does not harm the eyes. The risk from a missed examination is incomparably higher.
Does retinopathy always require treatment?+
No. Mild stages often go away on their own as the vessels mature, and the doctor limits himself to observation. Treatment is carried out when the threshold stage is reached, and then it should be carried out in the coming days.
Do I need to be monitored after recovery?+
Yes. Children who have retinopathy of prematurity are more likely to have myopia, strabismus, amblyopia, and an increased risk of glaucoma. Regular examinations by an ophthalmologist in preschool and school age allow you to select a correction in a timely manner.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated retinopathy of prematurity в Ташкенте

Ретинопатию находят только при осмотре глазного дна в строго определённые сроки, и это единственный способ не упустить время. Clinics Ташкента с детскими офтальмологами:

st. Mirzaeva 50, Yunusabad 17, Yunusabad district, Tashkent Landmark: opposite the Nazar M...
M Turkiston 🚶 1.5 km
M Yunusobod 🚶 2.0 km
M Shahriston 🚶 2.8 km
🚌 Nearest bus stop 🚶 100 m · buses: 7
Mon–Fri:09:00–18:00
Closed now
Tashkent, Almazar district, st. Langar 9 dead end, 2B
M Chorsu 🚶 700 m
M Tinchlik 🚶 1.2 km
M G'afur G'ulom 🚶 1.7 km
🚌 Nearest bus stop 🚶 180 m · buses: 5, 11, 23, 28, 29
Mon–Fri:08:30–17:00
Closed now
Tashkent, Shaykhantakhur district, st. Mannon Uygur, 290d
M Paxtakor 🚶 450 m
M Mustaqillik maydoni 🚶 700 m
M Alisher Navoiy 🚶 800 m
🚌 Nearest bus stop 🚶 120 m · buses: 51
Mon–Fri:09:00–17:00
Closed now
Tashkent, Chilanzar district, st. Kichik Khalka Yuli, 14d
M Mirzo Ulug'bek 🚶 2.2 km
M Chilonzor 🚶 2.4 km
M Novza 🚶 2.5 km
🚌 Nearest bus stop 🚶 80 m · buses: 34
Mon–Fri:09:00–17:00
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Tashkent, Mirabad district. st. Banokatiy, 186d
M Toshkent 🚶 1.3 km
M Mashinasozlar 🚶 1.7 km
M Oybek 🚶 2.5 km
🚌 Nearest bus stop 🚶 150 m · buses: 13Т, 22, 26
Mon–Fri:09:00–17:00
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Tashkent, Almazar district, st. Ziyo Said, 12d
M Olmazor 🚶 700 m
M Chilonzor 🚶 1.2 km
M Mirzo Ulug'bek 🚶 2.2 km
🚌 Nearest bus stop 🚶 110 m · buses: 8, 41
Mon–Fri:09:00–17:00
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Tashkent, Almazar district, Sebzor massif, Ts 17/18, 1d
M G'afur G'ulom 🚶 900 m
M Chorsu 🚶 1.2 km
M Alisher Navoiy 🚶 1.4 km
🚌 Nearest bus stop 🚶 260 m · buses: 17, 43
Пн–Sun:08:00–24:00
Open now

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

Other diseases: Ophthalmology

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