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Endophthalmitis: inflammation inside the eye where there is no time to waste

Other names: Эндофтальмит, гнойное воспаление внутри глаза, воспаление стекловидного тела, эндофтальмит после операции катаракты, инфекция глаза после инъекции

Endophthalmitis is a severe inflammation of the inner membranes and cavities of the eye, most often caused by bacteria or fungi. The pathogen gets inside during a penetrating injury, after surgery or intraocular injection, or less often through the bloodstream from another source of infection. There are almost no barriers inside the eye to hold back microbes, so inflammation develops rapidly: within hours, vision can drop to light perception. Typical signs are rapidly increasing pain, redness, blurred vision, and pus in the anterior chamber. This is a condition in which the hours are counted: the earlier treatment is started, the higher the chance of maintaining vision. With such symptoms, you should immediately seek ophthalmological help.

🧾 МКБ-10: H44.0 🏥 Where it is treated: 6 The clock is countingMost often after surgery or injuryImmediately see an ophthalmologist
👨‍⚕️ Which doctor
Ophthalmologist, vitreoretinal surgeon
🔬 Diagnostics
Slit lamp examination, visual acuity test, B-scan ultrasound of the eye, intraocular fluid culture with sensitivity determination
💊 Treatment
Administration of antibiotics into the eye, vitrectomy according to indications, systemic and local therapy
📈 Prognosis
Depends on the pathogen and the speed of initiation of treatment; delay leads to loss of vision
⚠️ At risk
Eye surgeries, intraocular injections, penetrating wounds, severe corneal ulcers, diabetes mellitus, immunodeficiency
⏱ When to see a doctor
Emergency

🚨 See a doctor urgently

With these signs do not wait for a scheduled appointment — the condition requires emergency care.

  • Резкое снижение зрения в течение нескольких часов
  • Нарастающая боль в глазу и головная боль
  • Выраженное покраснение глаза, отёк век
  • Уровень гноя в передней камере глаза, мутный зрачок
  • Появление или усиление плавающих помутнений и вспышек
  • Любые of этих признаков после операции или укола в глаз — немедленно к офтальмологу или 103

How does infection get inside the eye?

Most often, the pathogen penetrates from the outside through the damaged membrane of the eye. This may be a surgical incision after cataract removal, a puncture during an intraocular injection, a wound due to trauma, or a corneal ulcer. This variant is called exogenous, and it accounts for the vast majority of cases. Less commonly, microorganisms are brought by blood from a distant focus - in sepsis, inflammation of the inner lining of the heart, abscesses, in people with intravenous catheters; this option is called endogenous, it is often bilateral and requires searching for the source of infection throughout the body.

  • After eye surgery, most often cataract
  • After intraocular injection
  • For penetrating wounds and foreign bodies
  • For severe corneal ulcers
  • Endogenous route - transfer with blood
  • Fungal forms develop more slowly

Symptoms

The classic picture of acute endophthalmitis appears in the first days after surgery or injury. The eye turns red, deep pain increases, the eyelids swell, vision quickly deteriorates - down to the ability to only distinguish light. Patients report fog, floaters, and photophobia. Upon examination, the doctor sees clouding of the intraocular media and often a level of pus in the anterior chamber. It is important to remember: slight discomfort and redness in the first days after surgery are normal, but increased pain along with decreased vision is always a reason for immediate treatment.

  • Rapid loss of vision
  • Increasing pain in the eye
  • Redness of the eye and swelling of the eyelids
  • Photophobia and lacrimation
  • Floaters, fog before the eye
  • Pus in the anterior chamber of the eye

Diagnostics

The diagnosis is made by an ophthalmologist based on the clinical picture during examination at a slit lamp, always with checking visual acuity and measuring intraocular pressure. If cloudiness of the media does not allow the fundus to be seen, an ultrasound examination of the eye is performed, which shows inflammatory changes in the vitreous and excludes retinal detachment. To select an accurate treatment, a sample of the intraocular fluid is taken for culture and sensitivity to antibiotics - the collection is performed simultaneously with the administration of the drug. With the endogenous variant, they additionally look for the source of infection in the body.

  • Slit lamp examination
  • Checking visual acuity and intraocular pressure
  • Ultrasound of the eye in B-scan mode
  • Collection of intraocular fluid for culture
  • Determination of sensitivity to antibiotics
  • Search for the source of infection in the endogenous form

Treatment

The basis of treatment is the introduction of antibiotics directly into the eye cavity: this is the only way to create the required concentration of the drug where the infection develops. In severe cases and very low vision, vitrectomy is performed - removal of the affected vitreous body with simultaneous administration of drugs. Additionally, drops and sometimes systemic medications are prescribed. Anti-inflammatory therapy is included according to the doctor’s decision. If it is fungal in nature, antifungal agents are used and treatment lasts longer. Self-medication with drops at home is unacceptable: it only wastes time.

  • Injecting antibiotics into the eye
  • Vitrectomy for severe cases
  • Local drop therapy
  • Systemic antibiotics for the endogenous form
  • Antifungal drugs for fungal infections
  • Treatment in an ophthalmological hospital

Prevention and prognosis

The risk of endophthalmitis after elective eye surgery is very low due to eye antiseptic treatment, sterile conditions and prophylactic antibiotic administration. A lot depends on the patient: strictly follow the instillation regimen, do not rub the eyes, do not swim in open reservoirs and pools in the early period, and come for examinations. If you have an eye injury, you should not try to remove the foreign body yourself - you need to cover the eye with a clean bandage and immediately consult a doctor. The prognosis depends on the pathogen and the time of treatment: part of the vision can be preserved in a significant proportion of patients if help is provided quickly.

  • Compliance with prescriptions after eye surgery
  • Do not rub your eye and protect it from water
  • Timely follow-up inspections
  • Immediate treatment for pain and loss of vision
  • In case of injury, cover your eye with a bandage and go to the doctor.
  • Treatment of chronic foci of infection and control of diabetes mellitus

Services and prices for this diagnosis

Based on official price lists of Tashkent clinics. The exact cost is determined after examination.

💊 Treatment

Frequently asked questions: Endophthalmitis

How urgently do you need to see a doctor?+
Immediately, at the same hour. Intraocular infection destroys the retina very quickly, and the prognosis directly depends on when treatment is started. You cannot wait until the morning or until a scheduled appointment if you have pain and decreased vision.
Is vision always lost?+
No. The outcome depends on the aggressiveness of the pathogen and the speed of treatment. With early administration of an antibiotic into the eye, a significant proportion of patients are able to maintain useful vision, although it may be lower than before.
Does this often happen after cataract surgery?+
Very rare: Modern cataract surgery is performed under sterile conditions with antibiotic prophylaxis. That is why any increase in pain and deterioration in vision after surgery is taken seriously by doctors and requires examination.
Is it possible to get by with drops?+
No. The drops do not penetrate into the eye in sufficient concentration, so for endophthalmitis they serve only as a supplement. The main treatment is the introduction of an antibiotic directly into the eye cavity, and in severe cases, vitrectomy.
Can endophthalmitis develop without surgery or trauma?+
Yes, with the endogenous version, the infection enters the eye with blood from another source - for example, with sepsis, inflammation of the heart valves, abscesses. Such cases require not only eye treatment, but also a search for the source of infection.

The information on this page is for reference only and does not replace a doctor consultation. Only a qualified specialist can make a diagnosis and prescribe treatment after an in-person examination.

Where it is treated endophthalmitis в Ташкенте

При подозрении на эндофтальмит помощь нужна в тот же день — откладывать визит нельзя. Clinics Ташкента с офтальмологами:

Tashkent, Almazar district, st. Langar 9 dead end, 2B
M Chorsu 🚶 700 m
M Tinchlik 🚶 1.2 km
M G'afur G'ulom 🚶 1.7 km
🚌 Nearest bus stop 🚶 180 m · buses: 5, 11, 23, 28, 29
Mon–Fri:08:30–17:00
Closed now
Tashkent, Shaykhantakhur district, st. Mannon Uygur, 290d
M Paxtakor 🚶 450 m
M Mustaqillik maydoni 🚶 700 m
M Alisher Navoiy 🚶 800 m
🚌 Nearest bus stop 🚶 120 m · buses: 51
Mon–Fri:09:00–17:00
Closed now
Tashkent, Chilanzar district, st. Kichik Khalka Yuli, 14d
M Mirzo Ulug'bek 🚶 2.2 km
M Chilonzor 🚶 2.4 km
M Novza 🚶 2.5 km
🚌 Nearest bus stop 🚶 80 m · buses: 34
Mon–Fri:09:00–17:00
Closed now
Tashkent, Mirabad district. st. Banokatiy, 186d
M Toshkent 🚶 1.3 km
M Mashinasozlar 🚶 1.7 km
M Oybek 🚶 2.5 km
🚌 Nearest bus stop 🚶 150 m · buses: 13Т, 22, 26
Mon–Fri:09:00–17:00
Closed now
Tashkent, Almazar district, st. Ziyo Said, 12d
M Olmazor 🚶 700 m
M Chilonzor 🚶 1.2 km
M Mirzo Ulug'bek 🚶 2.2 km
🚌 Nearest bus stop 🚶 110 m · buses: 8, 41
Mon–Fri:09:00–17:00
Closed now
Tashkent, Almazar district, Sebzor massif, Ts 17/18, 1d
M G'afur G'ulom 🚶 900 m
M Chorsu 🚶 1.2 km
M Alisher Navoiy 🚶 1.4 km
🚌 Nearest bus stop 🚶 260 m · buses: 17, 43
Пн–Sun:08:00–24:00
Closed now

ICD-10 code

Official international classification codes — these are used in medical records and statistics.

Other diseases: Ophthalmology

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